Markers of Bone Turnover in Gaucher Disease: Modeling the Evolution of Bone Disease
نویسندگان
چکیده
منابع مشابه
Bone turnover markers in patients with type 1 Gaucher disease
Bone complications occur frequently in Gaucher disease (GD) and reduce the quality of life of these patients. Skeletal involvement is an important indication for treatment to ameliorate symptoms and reduce the risk of irreversible and debilitating disease. Bone biomarkers have been used to assess disease status and the response to therapy in a number of bone disorders. Here, we examine the lite...
متن کاملBone events and evolution of biologic markers in Gaucher disease before and during treatment
INTRODUCTION Known biomarkers of Gaucher-disease activity are platelets, chitotriosidase, angiotensin-converting enzyme (ACE), tartrate-resistant acid phosphatase (TRAP) and ferritin. The aim of this study was to retrospectively evaluate the frequency of bone events (BE) and biomarker changes during two periods: diagnosis to first enzyme-replacement therapy (ERT) and the latter to the closing d...
متن کاملMarkers of bone turnover in prepubertal children with celiac disease.
1. Liaw YF, Sheen IS, Chen TJ, Chu CM, Pao CC. Incidence determinants and significance of delayed clearance of serum HBsAg in chronic hepatitis B virus infection: a prospective study. Hepatology 1991;13:627-31. 2. Agarwal N, Naik S, Aggarwal R, Singh H, Somani SK, Kini D, et al. Occult hepatitis B virus infection as a cause of cirrhosis of liver in a region with intermediate endemicity. Indian ...
متن کاملBiochemical markers of bone turnover in patients with metastatic bone disease.
Several biochemical markers of bone formation and bone resorption have recently been developed. These markers have been evaluated for clinical utility in patients with metabolic bone disease, including Paget disease and osteoporosis, and for their potential use in cancer patients whose disease has metastasized to bone. We have evaluated seven markers of bone turnover in the plasma and urine of ...
متن کاملBone turnover markers.
Bones are constantly remodelled to cope with the body's calcium requirements and to repair microscopic damage. The entire skeleton is replaced every 10 years in adults, and around 10% of the skeleton is involved in bone remodelling at any one time.
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2011
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2011-0162